While base editors are too new to have already entered human clinical trials, scientists have succeeded in achieving a critical milestone towards that goal by using base editors in animals to correct point mutations that cause human genetic diseases.

虽然碱基编辑太新了，还不足以进入人类临床试验，但科学家们已经成功地实现了这一目标，即在动物身上使用碱基编辑来纠正导致人类遗传病的点突变。

And while it may still be several years before some of the more ambitious applications are proven to work—such as using CRISPR to cure genetic diseases—CRISPR has proven indisputably useful as a research tool.

尽管可能还需几年时间去证实CRISPR有更大的用处，比如使用CRISPR来治疗遗传疾病，但作为一种研究工具，它已经被证明肯定是有用的。

And as reporter Fergus Walsh said at the end of the clip, gene editing could be important for treating or even curing inherited genetic diseases.

如我们的记者费格斯·沃尔什最后所说，基因编辑对于治疗甚至治愈遗传疾病很。

More and more doctors believe that cancer is a genetic disease.

越来越多医生认为癌症是遗传病。

That might allow a permanent fix for some genetic diseases. World news from the BBC.

那么这将有助于治疗遗传疾病。BBC全球新闻。

Gene therapy is when DNA is introduced into a patient to treat a genetic disease.

基因治疗是将 DNA 引入患者体内以治疗遗传病。

Alzheimer's isn't, for the most part, a genetic disease.

阿兹海默症大多不是由遗传因素导致的。

Some congenital causes of primary hypogonadism are genetic diseases like Klinefelter or Turner syndrome.

可引起原发性性腺功能减退的先天因素包括Klinefelter综合征或Turner综合征等遗传病。

She has a rare genetic disease that killed two of her sisters.

她患有一种罕见的遗传病，这种遗传病导致她的两个姐姐死亡。

This means genetic diseases such as haemophilia, muscular dystrophy and cancers, in principle, might be " corrected" by editing the DNA of human embryos.

这意味着血友病、肌肉萎缩症和癌症等遗传疾病原则上可以通过编辑人类胚胎的 DNA 得到“纠正”。

As a quick recap: sickle cell disease is an autosomal recessive genetic disease where the beta-globin subunit of hemoglobin is misshapen, which causes red blood cells to sickle when deoxygenated.

好！简回顾一下：镰状细胞病，是常染色体隐性遗传病，其中血红蛋白的β-珠蛋白发生突变，脱氧情况下会导致红细胞镰变。

Perhaps we should look at Fatal Familial Insomnia, a rare genetic disease of the brain, which causes progressively worsening insomnia or sleeplessness leading to hallucinations, dementia and ultimately, death.

我们应该再看看致命的家族性失眠。这是一种罕见的脑部遗传性疾病，它会引发越来越严的失眠或由失眠引起的幻觉、痴呆，最终导致死亡。

Editing the unhealthy cells of those suffering from genetic diseases such as Duchenne's muscular dystrophy and cystic fibrosis will alleviate their suffering.

编辑那些患有杜氏肌营养不良和囊性纤维化等遗传疾病的人的不健康细胞将减轻患者痛苦。

Also, people with the genetic disease DiGeorge syndrome, often born with parathyroid glands that are too small and can't produce enough parathyroid hormone.

或是由于患有DiGeorge综合症，生来甲状旁腺就太小，不能产生足够的甲状旁腺激素。

So I think when we think as genome engineers about what should we work on, it's really about these genetic diseases.

所以我认为，作为基因组工程师，当我们思考我们应该做什么时，实际上应该专注于这些遗传疾病。

SMA is a genetic disease that slowly destroys motor neurons, nerve cells in the spinal cord that control muscles.

SMA是一种遗传性疾病，它会慢慢破坏运动神经元，即脊髓中控制肌肉的神经细胞。

Doctors want to create babies from two women and one man in order to prevent deadly genetic diseases.

医生们希望用两名妇女和一名男子来制造婴儿，希望能避免致命的遗传疾病。

Additional work lies ahead before base editing can realize its full potential to improve the lives of patients with genetic diseases.

在碱基编辑能够充发挥其改善遗传病患者生活的潜力之前，还有其他工作做。

Or it can repair the code by inserting a healthy copy of the gene. These techniques raise the prospect of treating – even curing – some genetic diseases – and it's not science fiction.

或者基因编辑通过在DNA链中插入健康基因片段来修复编码。这些技术增加了治疗甚至治愈基因性疾病的可能，这并非科幻。

One day it may make sense to edit an embryo-to cure genetic diseases, say.

也许有一天编辑胚胎是有意义的——比如说，用来治疗遗传疾病。